ea0035p956 | Steroid metabolism and action | ECE2014
Kancheva Radmila
, Hill Martin
, Kancheva Lyudmila
, Velikova Marta
, Pavelcova Miluse
, Starka Luboslav
, Havrdova Eva
Some steroids modulate the permeability of ionotropic receptors on cell membranes and therefore may activate or inhibit neuronal activity depending on the steroid structure. These neuroactive steroids (NAS) exert neuroprotective effects like the neuronal remyelination.Multiple sclerosis (MS) is the most common cause of neurological disability in young adults. Therefore, the authors have followed the neuroprotective, GABAergic, glycinergic, glutamatergic ...